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Chemical Fusion is the act of combining a Loud G-Stone-equipped program (namely Palparepa) with a large object resembling the traditional model of a molecule, shattering the latter into particles that reconsolidate into the form of a Mechanoid (namely Palparepa PLUS).
Palparepa's Chemical Fusion sequence was different in each of its appearances - the first had very different sound effects, which had a more alien tone to them, and the Loud G-Stone symbol on the head attachment was not made visible in this version (so as to add additional shock value near the end of Episode 4 of FINAL). Palparepa himself also sounds more agitated when speaking his own name during the second rendition.